Saracin health benefit
Saracin, a seed integument lectin from Saraca indica is highly specific for binding N-acetyl-neuraminyl-N-acetyllactosamine.
Saracin: A lectin from Saraca indica seed integument induces apoptosis in
human T-lymphocytes.
Arch Biochem Biophys. 1999 November. Ghosh S, Majumder M, Majumder S, Ganguly NK,
Chatterjee BP. Department of Experimental Medicine and Biotechnology, Post
Graduate Institute of Medical Education and Research, Chandigarh, 160 012,
India.
Sarasin lectin has been found to be mitogenic for human lymphocytes. Treatment
with saracin induces secretion of IL-2 in a culture of resting human peripheral
blood mononuclear cells. Saracin has a higher affinity for the CD8(+) than
CD4(+) T cells. Saracin seems to be an interesting immunomodulator for the
mammalian immune system. Copyright 1999 Academic Press.
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