Salatrim information

Salatrim is modified triacylglycerol that is rich in short-chain fatty acids and stearic acid. Salatrim is used as a lower-calorie fat replacer.

Salatrim and weight loss
Some people claim that salatrim has a reduced absorption in the small intestine which may lead to greater amounts of fat in the gastrointestinal tract, which may decrease appetite and energy intake through the release of appetite-regulating gastrointestinal hormones. Studies show that Salatrim had a modestly more suppressive effect on appetite than does a traditional fat. Gastrointestinal hormones do not appear to be involved.

The effect of salatrim, a low-calorie modified triacylglycerol, on appetite and energy intake.
Am J Clin Nutr. 2008 May; Sørensen LB, Cueto HT, Andersen MT, Bitz C, Holst JJ, Rehfeld JF, Astrup A. Department of Human Nutrition, Centre for Advanced Food Studies, Faculty of Life Sciences, University of Copenhagen, Copenhagen, Denmark.
Salatrim has been hypothesized to reduce absorption in the small intestine may lead to greater amounts of fat in the gastrointestinal tract, which may decrease appetite and energy intake through the release of appetite-regulating gastrointestinal hormones. We aimed to compare the effects of salatrim and traditional fat on appetite, ad libitum energy intake, and gastrointestinal hormones. Twenty-two healthy, young, normal-weight men participated in a randomized, double-blind, crossover study. Test meals were a traditional fat meal and a salatrim meal with a mixture of traditional fat and salatrim. The salatrim meal increased fullness and decreased hunger significantly more than did the traditional fat meal. The traditional fat meal increased well-being. There was no significant difference in ad libitum energy intake or overall energy intake between the 2 test days. No significant differences in blood glucose, insulin, triacylglycerol, ghrelin, cholecystokinin, glucagon-like peptide-1, or peptide YY concentrations were found. A significantly smaller increase in free fatty acids was observed after the salatrim meal than after the traditional fat meal. Salatrim had a modestly more suppressive effect on appetite than did a traditional fat. Gastrointestinal hormones did not seem to be involved.

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